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1

Functional characteristics of CRH receptors and potential clinical applications of CRH-receptor antagonists

Dimitris K. Grammatopoulos, George P. Chrousos

Journal:

Trends in Endocrinology & Metabolism

Year:

2002

Language:

english

File:

PDF, 359 KB

english, 2002

2

The identification of mitochondrial DNA variants in glioblastoma multiforme

Yeung, Ka, Dickinson, Adam, Donoghue, Jacqueline F, Polekhina, Galina, White, Stefan J, Grammatopoulos, Dimitris K, McKenzie, Matthew, Johns, Terrance G, John, Justin

Journal:

Acta Neuropathologica Communications

Year:

2014

Language:

english

File:

PDF, 1.86 MB

english, 2014

3

Determining the stress biomarker profile in patients undergoing total knee replacement and the relationship with outcome at 12 months

Chawla, Amit, Paraoan, Vlad, Rabiu, Rasheed, Clark, Tamsyn, Powell, Sam, Grammatopoulos, Dimitris, Armitage, Charlotte, Penedo, Ana, Havard, Alwyn, Metcalfe, Andrew, Barlow, Tim, Khatri, Chetan

Journal:

Year:

2019

File:

PDF, 647 KB

2019

4

Potential signalling pathways underlying corticotrophin-releasing hormone-mediated neuroprotection from excitotoxicity in rat hippocampus

Caroline R. Elliott-Hunt, Jurate Kazlauskaite, Geraint J. C. Wilde, Dimitris K. Grammatopoulos, Edward W. Hillhouse

Journal:

Journal of Neurochemistry

Year:

2002

Language:

english

File:

PDF, 342 KB

english, 2002

5

Rat cerebral cortex corticotropin-releasing hormone receptors: evidence for receptor coupling to multiple G-proteins

Dimitris K. Grammatopoulos, Harpal S. Randeva, Michael A. Levine, Korinna A. Kanellopoulou, Edward W. Hillhouse

Journal:

Journal of Neurochemistry

Year:

2001

Language:

english

File:

PDF, 703 KB

english, 2001

6

Association of the 894G>T polymorphism in the endothelial nitric oxide synthase gene with risk of acute myocardial infarction

George K Andrikopoulos, Dimitris K Grammatopoulos, Stylianos E Tzeis, Sevasti I Zervou, Dimitris J Richter, Michalis N Zairis, Elias J Gialafos, Dimitris C Sakellariou, Stefanos G Foussas, Antonis S M

Journal:

BMC Medical Genetics

Year:

2008

Language:

english

File:

PDF, 233 KB

english, 2008

7

Pathological interactions with the timing of birth and uterine activation

Roger SMITH, Dirk VAN HELDEN, Jon HIRST, Tamas ZAKAR, Mark READ, Eng-Cheng CHAN, Hannah PALLISER, Dimitris GRAMMATOPOULOS, Richard NICHOLSON, Helena C. PARKINGTON

Journal:

Australian and New Zealand Journal of Obstetrics and Gynaecology

Year:

2007

Language:

english

File:

PDF, 207 KB

english, 2007

8

Molecular determinants and feedback circuits regulating type 2 CRH receptor signal integration

Danijela Markovic, Anu Punn, Hendrik Lehnert, Dimitris K. Grammatopoulos

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

2011

Language:

english

File:

PDF, 1.31 MB

english, 2011

9

Structural domains determining signalling characteristics of the CRH-receptor type 1 variant R1β and response to PKC phosphorylation

Thalia Teli, Danijela Markovic, Margaret E. Hewitt, Michael A. Levine, Edward W. Hillhouse, Dimitris K. Grammatopoulos

Journal:

Cellular Signalling

Year:

2008

Language:

english

File:

PDF, 1.32 MB

english, 2008

10

Focus on the splicing of Secretin GPCRs transmembrane-domain 7

Danijela Markovic, Dimitris K. Grammatopoulos

Journal:

Trends in Biochemical Sciences

Year:

2009

Language:

english

File:

PDF, 775 KB

english, 2009

11

Insights into mechanisms of corticotropin-releasing hormone receptor signal transduction

Dimitris K Grammatopoulos

Journal:

British Journal of Pharmacology

Year:

2012

Language:

english

File:

PDF, 1.87 MB

english, 2012

12

Hormonal regulation of placental nitric oxide and pathogenesis of pre-eclampsia

Manu Vatish, Harpal S. Randeva, Dimitris K. Grammatopoulos

Journal:

Trends in Molecular Medicine

Year:

2006

Language:

english

File:

PDF, 4.11 MB

english, 2006

13

Role of corticotropin-releasing hormone in onset of labour

Dimitris K Grammatopoulos, Edward W Hillhouse

Journal:

Year:

1999

Language:

english

File:

PDF, 74 KB

english, 1999

14

The 894G T polymorphism in the endothelial nitric oxide synthase gene influences risk for acute myocardial infarction only in subjects with low risk for coronary events

George K. Andrikopoulos, Dimitri Richter, Dimitri Grammatopoulos, Sevasti Zervou, Michalis Zairis, Elias Karabinos, Antonis Pantazis, Dimitris Manolatos, Nikolaos Exadaktylos, Christodoulos Stefanadis

Journal:

Journal of the American College of Cardiology

Year:

2002

Language:

english

File:

PDF, 174 KB

english, 2002

15

Cyclic AMP increases COX-2 expression via mitogen-activated kinase in human myometrial cells

Li Chen, Suren R. Sooranna, Kaiyu Lei, Mandeep Kandola, Phillip R. Bennett, Zhiqing Liang, Dimitri Grammatopoulos, Mark R. Johnson

Journal:

Journal of Cellular and Molecular Medicine

Year:

2012

Language:

english

File:

PDF, 535 KB

english, 2012

16

Corticotropin-Releasing Hormone Interacts With Interleukin-1β to Regulate Prostaglandin H Synthase-2 Expression in Human Myometrium During Pregnancy and Labor

Markovic, Danijela, Bari, Muhammad F., Lu, Buyu, Vatish, Manu, Grammatopoulos, Dimitris K.

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2013

Language:

english

File:

PDF, 430 KB

english, 2013

17

Cyclic AMP enhances progesterone action in human myometrial cells

Chen, Li, Lei, Kaiyu, Malawana, Johann, Yulia, Angela, Sooranna, Suren R., Bennett, Phillip R., Liang, Zhiqing, Grammatopoulos, Dimitri, Johnson, Mark R.

Journal:

Molecular and Cellular Endocrinology

Year:

2014

Language:

english

File:

PDF, 1.62 MB

english, 2014

18

Authors response to stergiakouli et al.

Kandala, Ngianga-Bakwin, Engineer, Neelam, Grammatopoulos, Dimitris

Journal:

Journal of Psychiatric Research

Year:

2014

Language:

english

File:

PDF, 151 KB

english, 2014

19

Association of glucocorticoid and type 1 corticotropin-releasing hormone receptors gene variants and risk for depression during pregnancy and post-partum

Engineer, Neelam, Darwin, Lucy, Nishigandh, Deole, Ngianga-Bakwin, Kandala, Smith, Steve C., Grammatopoulos, Dimitris K.

Journal:

Journal of Psychiatric Research

Year:

2013

Language:

english

File:

PDF, 1.03 MB

english, 2013

20

Extra-nuclear telomerase reverse transcriptase (TERT) regulates glucose transport in skeletal muscle cells

Shaheen, Fozia, Grammatopoulos, Dimitris K., Müller, Jürgen, Zammit, Victor A., Lehnert, Hendrik

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2014

Language:

english

File:

PDF, 1.44 MB

english, 2014

21

Intracellular Mechanisms Regulating Corticotropin-Releasing Hormone Receptor-2β Endocytosis and Interaction with Extracellularly Regulated Kinase 1/2 and p38 Mitogen-Activated Protein Kinase Signaling Cascades

Markovic, Danijela, Punn, Anu, Lehnert, Hendrik, Grammatopoulos, Dimitris K.

Journal:

Molecular Endocrinology

Year:

2008

Language:

english

File:

PDF, 1.60 MB

english, 2008

22

Preeclampsia Is Associated with Impaired Regulation of the Placental Nitric Oxide-Cyclic Guanosine Monophosphate Pathway by Corticotropin-Releasing Hormone (CRH) and CRH-Related Peptides

Karteris, Emmanouil, Vatish, Manu, Hillhouse, Edward W., Grammatopoulos, Dimitris K.

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2005

Language:

english

File:

PDF, 453 KB

english, 2005

23

Activation of Protein Kinase C by Oxytocin Inhibits the Biological Activity of the Human Myometrial Corticotropin-Releasing Hormone Receptor at Term 1

Grammatopoulos, Dimitris K., Hillhouse, Edward W.

Journal:

Year:

1999

Language:

english

File:

PDF, 401 KB

english, 1999

24

Identification of a Novel Corticotropin-Releasing Hormone Type 1β-Like Receptor Variant Lacking Exon 13 in Human Pregnant Myometrium Regulated by Estradiol-17β and Progesterone

Karteris, Emmanouil, Markovic, Danijela, Chen, Jing, Hillhouse, Edward W., Grammatopoulos, Dimitris K.

Journal:

Year:

2010

Language:

english

File:

PDF, 333 KB

english, 2010

25

CRH-R splicing in estrogen-sensitive breast cancer

Grammatopoulos, Dimitris K

Journal:

Year:

2014

Language:

english

File:

PDF, 703 KB

english, 2014

26

A Novel Spliced Variant of the Type 1 Corticotropin-Releasing Hormone Receptor with a Deletion in the Seventh Transmembrane Domain Present in the Human Pregnant Term Myometrium and Fetal Membranes

Grammatopoulos, Dimitris K., Dai, Yalei, Randeva, Harpal S., Levine, Michael A., Karteris, Emmanouil, Easton, Andrew J., Hillhouse, Edward W.

Journal:

Molecular Endocrinology

Year:

1999

Language:

english

File:

PDF, 2.23 MB

english, 1999

27

Structural Determinants Critical for Localization and Signaling within the Seventh Transmembrane Domain of the Type 1 Corticotropin Releasing Hormone Receptor: Lessons from the Receptor Variant R1d

Markovic, Danijela, Lehnert, Hendrik, Levine, Michael A., Grammatopoulos, Dimitris K.

Journal:

Molecular Endocrinology

Year:

2008

Language:

english

File:

PDF, 1.04 MB

english, 2008

28

Urocortin II Is Expressed in Human Pregnant Myometrial Cells and Regulates Myosin Light Chain Phosphorylation: Potential Role of the Type-2 Corticotropin-Releasing Hormone Receptor in the Control of Myometrial Contractility

Karteris, Emmanouil, Hillhouse, Edward W., Grammatopoulos, Dimitris

Journal:

Year:

2004

Language:

english

File:

PDF, 559 KB

english, 2004

29

Basal and Interleukin-1β-Stimulated Prostaglandin Production from Cultured Human Myometrial Cells: Differential Regulation by Corticotropin- Releasing Hormone 1

Grammatopoulos, Dimitris K., Hillhouse, Edward W.

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

1999

Language:

english

File:

PDF, 1.09 MB

english, 1999

30

Protein Kinase A-Induced Negative Regulation of the Corticotropin-Releasing Hormone R1α Receptor-Extracellularly Regulated Kinase Signal Transduction Pathway: The Critical Role of Ser 301 for Signaling Switch and Selectivity

Papadopoulou, Nikolleta, Chen, Jing, Randeva, Harpal S., Levine, Michael A., Hillhouse, Edward W., Grammatopoulos, Dimitris K.

Journal:

Molecular Endocrinology

Year:

2004

Language:

english

File:

PDF, 849 KB

english, 2004

31

Urocortin, but Not Corticotropin-Releasing Hormone (CRH), Activates the Mitogen-Activated Protein Kinase Signal Transduction Pathway in Human Pregnant Myometrium: An Effect Mediated via R1α and R2β CRH Receptor Subtypes and Stimulation of Gq-Proteins

Grammatopoulos, Dimitris K., Randeva, Harpal S., Levine, Michael A., Katsanou, Efrosini S., Hillhouse, Edward W.

Journal:

Molecular Endocrinology

Year:

2000

Language:

english

File:

PDF, 639 KB

english, 2000

32

Identification of Signaling Molecules Mediating Corticotropin-Releasing Hormone-R1α-Mitogen-Activated Protein Kinase (MAPK) Interactions: The Critical Role of Phosphatidylinositol 3-Kinase in Regulating ERK1/2 But Not p38 MAPK Activation

Punn, Anu, Levine, Michael A., Grammatopoulos, Dimitris K.

Journal:

Molecular Endocrinology

Year:

2006

Language:

english

File:

PDF, 1.47 MB

english, 2006

33

Human Corticotropin-Releasing Hormone Receptor: Differences in Subtype Expression between Pregnant and Nonpregnant Myometria 1

Grammatopoulos, Dimitris, Dai, Yalei, Chen, Jing, Karteris, Emmanouil, Papadopoulou, Nikoletta, Easton, Andrew J., Hillhouse, Edward W.

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

1998

Language:

english

File:

PDF, 1.15 MB

english, 1998

34

Regulation of Corticotropin-Releasing Hormone Receptor Type 1α Signaling: Structural Determinants for G Protein-Coupled Receptor Kinase-Mediated Phosphorylation and Agonist-Mediated Desensitization

Teli, Thalia, Markovic, Danijela, Levine, Michael A., Hillhouse, Edward W., Grammatopoulos, Dimitris K.

Journal:

Molecular Endocrinology

Year:

2005

Language:

english

File:

PDF, 824 KB

english, 2005

35

Hypertestosteronemia and Infertility from a Mediastinal Extragonadal Germ Cell Tumor

Dimitriadis, Georgios K., Kaltsas, Gregory, Ghobara, Tarek, Sinha, Bidisa, Drakou, Eftychia E., Gopalakrishnan, Kishore, Kosmas, Christos, Keay, Stephen D., Grammatopoulos, Dimitris K., Randeva, Harpa

Journal:

The American Journal of Medicine

Year:

2017

Language:

english

File:

PDF, 2.06 MB

english, 2017

36

Regulation of G-protein coupled receptor signalling underpinning neurobiology of mood disorders and depression

Grammatopoulos, Dimitris K

Journal:

Molecular and Cellular Endocrinology

Year:

2017

Language:

english

File:

PDF, 707 KB

english, 2017

37

Pleiotropic GPCR signaling in health and disease

Hanyaloglu, Aylin C., Grammatopoulos, Dimitris K.

Journal:

Molecular and Cellular Endocrinology

Year:

2017

Language:

english

File:

PDF, 153 KB

english, 2017

38

Actin Cytoskeleton-Dependent Regulation of Corticotropin-releasing Factor Receptor Heteromers

Hasdemir, Burcu, Mahajan, Shilpi, Oses-Prieto, Juan, Chand, Shreya, Woolley, Michael, Burlingame, Alma, Grammatopoulos, Dimitris K., Bhargava, Aditi, Heldin, Carl-Henrik

Journal:

Molecular Biology of the Cell

Year:

2017

Language:

english

File:

PDF, 1.68 MB

english, 2017

39

Metabolic phenotype of male obesity-related secondary hypogonadism pre-replacement and post-replacement therapy with intra-muscular testosterone undecanoate therapy

Dimitriadis, Georgios K., Randeva, Harpal S., Aftab, Saboor, Ali, Asad, Hattersley, John G., Pandey, Sarojini, Grammatopoulos, Dimitris K., Valsamakis, Georgios, Mastorakos, Georgios, Jones, T. Hugh,

Journal:

Endocrine (Springer)

Year:

2018

Language:

english

File:

PDF, 495 KB

english, 2018

40

Corticotropin-Releasing Factor Receptors Couple to Multiple G-Proteins to Activate Diverse Intracellular Signaling Pathways in Mouse Hippocampus: Role in Neuronal Excitability and Associative Learning

Blank, Thomas, Nijholt, Ingrid, Grammatopoulos, Dimitris K., Randeva, Harpal S., Hillhouse, Edward W., Spiess, Joachim

Journal:

Journal of Neuroscience

Year:

2003

Language:

english

File:

PDF, 392 KB

english, 2003

41

Corticotropin-Releasing Hormone As the Homeostatic Rheostat of Feto-Maternal Symbiosis and Developmental Programming In Utero and Neonatal Life

Alcántara-Alonso, Viridiana, Panetta, Pamela, de Gortari, Patricia, Grammatopoulos, Dimitris K.

Journal:

Frontiers in Endocrinology

Year:

2017

Language:

english

File:

PDF, 816 KB

english, 2017

42

Familial Hypercholesterolemia: New Horizons for Diagnosis and Effective Management

Mytilinaiou, Maria, Kyrou, Ioannis, Khan, Mike, Grammatopoulos, Dimitris K., Randeva, Harpal S.

Journal:

Frontiers in Pharmacology

Year:

2018

Language:

english

File:

PDF, 1.15 MB

english, 2018

43

Modelling of psychosocial and lifestyle predictors of peripartum depressive symptoms associated with distinct risk trajectories: a prospective cohort study

English, Sarah, Steele, Amber, Williams, Alison, Blacklay, Jayne, Sorinola, Olanrewaju, Wernisch, Lorenz, Grammatopoulos, Dimitris K.

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 1.65 MB

english, 2018

44

Improved Thyroid Hypoechogenicity Following Bariatric-Induced Weight Loss in Euthyroid Adults With Severe Obesity—a Pilot Study

Kyrou, Ioannis, Adesanya, Olu, Hedley, Nicholas, Wayte, Sarah, Grammatopoulos, Dimitris, Thomas, Claire L., Weedall, Andrew, Sivaraman, Subash, Pelluri, Lavanya, Barber, Thomas M., Menon, Vinod, Rande

Journal:

Frontiers in Endocrinology

Year:

2018

Language:

english

File:

PDF, 543 KB

english, 2018

45

Effects of intake of breakfast or caffeine-containing beverages on measurement of circulating chromogranin A in plasma

Robbins, Helen L., Symington, Megan, Mosterman, Barbara, Tranter, Fiona, Davies, Louise, Randeva, Harpal S., Penedo, Ana, Ferreira, Clara, Darby, Catherine, Grammatopoulos, Dimitri, Kaltsas, Gregory,

Journal:

Year:

2019

Language:

english

File:

PDF, 1.23 MB

english, 2019

46

Antenatal screening for fetal trisomies using microarray‐based cell‐free DNA testing – a systematic review and meta‐analysis

Geppert, Julia, Stinton, Chris, Johnson, Samantha, Clarke, Aileen, Grammatopoulos, Dimitris, Taylor‐Phillips, Sian

Journal:

Prenatal Diagnosis

Year:

2019

File:

PDF, 2.84 MB

2019

47

Involvement of the Endocrine-Disrupting Chemical Bisphenol A (BPA) in Human Placentation

de Aguiar Greca, Sophie-Christine, Kyrou, Ioannis, Pink, Ryan, Randeva, Harpal, Grammatopoulos, Dimitris, Silva, Elisabete, Karteris, Emmanouil

Journal:

Journal of Clinical Medicine

Year:

2020

File:

PDF, 6.71 MB

2020

48

Bacteriophage K1F targets Escherichia coli K1 in cerebral endothelial cells and influences the barrier function

MÃ¸ller-Olsen, Christian, Ross, Toby, Leppard, Keith N., Foisor, Veronica, Smith, Corinne, Grammatopoulos, Dimitris K., Sagona, Antonia P.

Journal:

Scientific Reports

Year:

2020

File:

PDF, 6.41 MB

2020

49

SUN-267 Dissecting Type 2 CRH Receptor Signaling Characteristics in the Hypothalamic Cell Line MHYPOA-2/30

Alcantara-Alonso, Viridiana, Gortari, Patricia de, Dallmann, Robert, Grammatopoulos, Dimitris

Journal:

Journal of the Endocrine Society

Year:

2020

File:

PDF, 91 KB

2020

50

Testing for lynch syndrome in people with endometrial cancer using immunohistochemistry and microsatellite instability-based testing strategies â A systematic review of test accuracy

Stinton, Chris, Fraser, Hannah, Al-Khudairy, Lena, Court, Rachel, Jordan, Mary, Grammatopoulos, Dimitris, Taylor-Phillips, Sian

Journal:

Gynecologic Oncology

Year:

2020

File:

PDF, 2.71 MB

2020

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